Insulin-like growth factor-I and binding protein-3 in relation to childhood leukaemia
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منابع مشابه
Insulin like growth factor-I, insulin like growth factor binding protein-1, and insulin in childhood Crohn's disease.
Twenty nine children with Crohn's disease were studied before and after treatment with steroids or an elemental diet to assess the effect of disease activity and treatment on serum insulin like growth factor I (IGF-I), insulin like growth factor binding protein (IGFBP-1), and insulin concentrations. The median serum IGF-I concentration was lower in patients with active disease than in matched c...
متن کاملBrain-derived neurotrophic factor, insulin-like growth factor-I and its binding protein responses to a session of endurance exercise in healthy elderly men
Purpose: This study investigated the effect of endurance activity on brain-derived neurotrophic factor(BDNF), insulin-like growth factor 1(IGF-1) and its binding protein 3(IGFBP-3) in elderly healthy individuals. Materials and Methods: Eleven healthy old males (mean age of 68 ± 2.31 years old, height of 177 ± 3.1 cm and weight of 79 ± 1.5 kg) were studied. Seventy two hours after maxi...
متن کاملInsulin-like growth factor I and insulin-like growth factor binding protein 5 in Crohn's disease.
Insulin-like growth factor (IGF)-I and its binding protein IGF binding protein 5 (IGFBP-5) were highly expressed in inflamed and fibrotic intestine in experimental Crohn's disease. IGF-I induced proliferation and increased collagen synthesis by smooth muscle cells and fibroblasts/myofibroblasts in vitro. Here we studied IGF-I and IGFBP-5 in Crohn's disease tissue. Tissue was collected from pati...
متن کاملEffects of alcohol on insulin-like growth factor I and insulin-like growth factor binding protein 3 in postmenopausal women.
BACKGROUND Increased circulating insulin-like growth factor I (IGF-I) concentrations, frequently adjusted for IGF binding protein 3 (IGFBP-3), have been associated with increased risk of several types of cancer, including colon, prostate, and breast. Studies have suggested that alcohol may affect IGF-I or IGFBP-3; however, controlled feeding studies to assess alcohol's effects on IGF-I or IGFBP...
متن کاملEffects of alcohol and menstrual cycle on insulin-like growth factor-I and insulin-like growth factor binding protein-3.
Alcohol ingestion and insulin-like growth factor-I (IGF-I) have been associated with increased breast cancer risk, the latter primarily in premenopausal women. We investigated whether alcohol ingestion altered IGF-I or its major binding protein (BP), IGFBP-3, in a controlled feeding study in premenopausal women. We also determined whether IGF-I or IGFBP-3 was affected by menstrual cycle phase. ...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1999
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19990209)80:4<494::aid-ijc2>3.0.co;2-k